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NUMB antibody

Anti-NUMB antibody used in Western Blot (WB). GTX31439
Anti-NUMB antibody used in IHC (Paraffin sections) (IHC-P). GTX31439
Anti-NUMB antibody used in IHC (Paraffin sections) (IHC-P). GTX31439

Cat. No. GTX31439

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all NUMB products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.25 - 0.5 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

Mouse Lung Tissue Lysate(GTX27933) , Human Lung Tissue Slide

Product Note

At least four isoforms of NUMB are known to exist; this antibody will detect all of them.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NUMB antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human NUMB.The immunogen is located within the last 50 amino acids of NUMB.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

NUMB endocytic adaptor protein , C14orf41 , S171 , c14_5527

Background

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-NUMB antibody used in Western Blot (WB). GTX31439

GTX31439 WB Image

WB analysis of mouse lung tissue lysate using GTX31439 NUMB antibody.
Working concentration : (A) 0.25 and (B) 0.5 μg/ml

Anti-NUMB antibody used in IHC (Paraffin sections) (IHC-P). GTX31439

GTX31439 IHC-P Image

IHC-P analysis of human lung tissue using GTX31439 NUMB antibody.
Working concentration : 20 μg/ml

Anti-NUMB antibody used in IHC (Paraffin sections) (IHC-P). GTX31439

GTX31439 IHC-P Image

IHC-P analysis of human lung tissue using GTX31439 NUMB antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399