GeneTex
United States (US)

NUMB antibody

GTX31439_2635_WB_20180221_18121410_647.jpg
GTX31439_1055_IHC-P_20180221_18121410_206.jpg
GTX31439_1056_IHC-P_20180221_18121410_796.jpg

Cat No. GTX31439

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.25 - 0.5 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

71 kDa. ( Note )

Positive Control

Mouse Lung Tissue Lysate(GTX27933) , Human Lung Tissue Slide

Specificity/Sensitivity

At least four isoforms of NUMB are known to exist; this antibody will detect all of them.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NUMB antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human NUMB.The immunogen is located within the last 50 amino acids of NUMB.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Numb, Endocytic Adaptor Protein,C14Orf41,S171,C14_5527,Numb

Background

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31439_2635_WB_20180221_18121410_647.jpg

GTX31439 WB Image

WB analysis of mouse lung tissue lysate using GTX31439 NUMB antibody.
Working concentration : (A) 0.25 and (B) 0.5 μg/ml

GTX31439_1055_IHC-P_20180221_18121410_206.jpg

GTX31439 IHC-P Image

IHC-P analysis of human lung tissue using GTX31439 NUMB antibody.
Working concentration : 5 μg/ml

GTX31439_1056_IHC-P_20180221_18121410_796.jpg

GTX31439 IHC-P Image

IHC-P analysis of human lung tissue using GTX31439 NUMB antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329