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Nav beta 2 antibody

Anti-Nav beta 2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54799
Anti-Nav beta 2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54799
Anti-Nav beta 2 antibody used in Western Blot (WB). GTX54799

Cat. No. GTX54799

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all Nav beta 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.75 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)KTEEEGKTDGEGNAEDGAK, corresponding to amino acid residues 197-215 (Intracellular, C-terminus) of voltage-gated Na+ channels (Accession  : P54900).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sodium voltage-gated channel beta subunit 2 , SCNB2

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

forms a voltage gated sodium channel with alpha subunit; may modulate sodium channel expression in neurons [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Nav beta 2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54799

GTX54799 IHC-Fr Image

IHC-Fr analysis of rat cerebellum tissue using GTX54799 Nav beta 2 antibody.
Panel A : NaVβ2 channel (red) appears in Purkinje cells (horizontal arrows) and is distributed diffusely in the molecular layer (Mol).
Panel B : Staining of Purkinje nerve cells with mouse anti-calcium binding protein (CBD28k, green) demonstrates the restriction of NaVβ2 to cell bodies.
Panel C : Merge of NaVβ2 and CBD28k.

Anti-Nav beta 2 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54799

GTX54799 IHC-Fr Image

IHC-Fr analysis of mouse cerebellum tissue using GTX54799 Nav beta 2 antibody.
Panel A : NaVβ2 channel (red) appears in Purkinje cells (vertical arrows) and in small cells in the molecular layer (horizontal arrows, Mol).
Panel B : Staining of Purkinje nerve cells with mouse anti-calcium binding protein (CBD28k, green) demonstrates the restriction of NaVβ2  to cell bodies.
Panel C : Merge of NaVβ2 and CBD28k.

Anti-Nav beta 2 antibody used in Western Blot (WB). GTX54799

GTX54799 WB Image

WB analysis of rat brain membranes lysate under reducing (lanes 1 and 2) or non-reducing (lanes 3 and 4) conditions using GTX54799 Nav beta 2 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639