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Nav1.2 antibody

Anti-Nav1.2 antibody used in IHC (Paraffin sections) (IHC-P). GTX66721
Anti-Nav1.2 antibody used in Western Blot (WB). GTX66721

Cat No. GTX66721

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

228 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 1002-1052 of Human Na+ CP type IIα.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

sodium voltage-gated channel alpha subunit 2 , BFIC3 , BFIS3 , BFNIS , EIEE11 , HBA , HBSCI , HBSCII , NAC2 , Na(v)1.2 , Nav1.2 , SCN2A1 , SCN2A2

Cellular Localization

Cell membrane

Background

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Database

Research Area

DATA IMAGES

Anti-Nav1.2 antibody used in IHC (Paraffin sections) (IHC-P). GTX66721

GTX66721 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66721 Nav1.2 antibody.
Dilution : 1:100

Anti-Nav1.2 antibody used in Western Blot (WB). GTX66721

GTX66721 WB Image

WB analysis of various samples using GTX66721 Nav1.2 antibody.
Lane1 : HEK293T whole cell lysate(40ug)
Lane2 : A549 whole cell lysate(40ug)
Lane3 : C6 whole cell lysate(40ug)
Lane4 : CT26 whole cell lysate(40ug)
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf