APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500-1:1000 |
1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide, corresponding to amino acids 1002-1052 of Human Na+ CP type IIα.
Purification
Purified by antigen-affinity chromatography
From serum
Purity
> 95% (by SDS-PAGE)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
sodium voltage-gated channel alpha subunit 2 , BFIC3 , BFIS3 , BFNIS , EIEE11 , HBA , HBSCI , HBSCII , NAC2 , Na(v)1.2 , Nav1.2 , SCN2A1 , SCN2A2
Cellular Localization
Cell membrane
Background
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Database
Research Area
DATA IMAGES
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GTX66721 IHC-P Image
IHC-P analysis of human breast carcinoma tissue using GTX66721 Nav1.2 antibody. Dilution : 1:100
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GTX66721 WB Image
WB analysis of various samples using GTX66721 Nav1.2 antibody. Lane1 : HEK293T whole cell lysate(40ug) Lane2 : A549 whole cell lysate(40ug) Lane3 : C6 whole cell lysate(40ug) Lane4 : CT26 whole cell lysate(40ug) Dilution : 1:1000
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REFERENCE
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REVIEW
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