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Nav1.6 antibody, Internal

Anti-Nav1.6 antibody, Internal used in Western Blot (WB). GTX47678
Anti-Nav1.6 antibody, Internal used in Western Blot (WB). GTX47678

Cat No. GTX47678

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human
Package
50 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
Not tested in other applications.

Calculated MW

225 kDa. ( Note )

Positive Control

human fetal muscle , NCI-H226

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human SCN8A

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

sodium voltage-gated channel alpha subunit 8 , BFIS5 , CERIII , CIAT , EIEE13 , MED , NaCh6 , Nav1.6 , PN4

Cellular Localization

Cell membrane

Background

This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Nav1.6 antibody, Internal used in Western Blot (WB). GTX47678

GTX47678 WB Image

WB analysis of human fetal muscle tissue using GTX47678 SCN8A antibody at 0.2-1μg/ml.

Anti-Nav1.6 antibody, Internal used in Western Blot (WB). GTX47678

GTX47678 WB Image

WB analysis of NCI-H226 cells using GTX47678 SCN8A antibody at 1μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf