Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Rat
Immunogen
Peptide CIANHTGVDIHRNGDFQKNG, corresponding to amino acid residues 1042-1061 (Intracellular loop between domains II and III) of rat NaV1.6 (Accession : O88420).
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
RRID
AB_2887892
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
sodium voltage-gated channel alpha subunit 8
Cellular Localization
Cell membrane
Background
tetrodotoxin-sensitive sodium channel alpha subunit [RGD, Feb 2006]
IHC-Fr analysis of mouse hippocampus tissue using GTX54842 Nav1.6 antibody. DAPI is used as the counterstain. Panel A : NaV1.6 (green) is robustly expressed in the CA1 pyramidal layer (white arrows). Panel B : Staining with mouse anti-parvalbumin (red), a marker of interneurons. Panel C : Merged image of panels A and B reveals that NaV1.6 appears in some interneurons (arrow) but is not restricted to interneurons.
Show More +
GTX54842 ICC/IF Image
ICC/IF analysis of PFA-fixed rat DRG primary cells using GTX54842 Nav1.6 antibody. Panel A : Primary antibody Panel B : DNA dye Hoechst 33342 Panel C : Merged images of panels A and B Dilution : 1:200
Show More +
GTX54842 WB Image
WB analysis of rat brain membrane lysates using GTX54842 Nav1.6 antibody preincubated with or without immunogen peptide. Dilution : 1:200
