GeneTex

  • Country / Location Selection

United States (US)

Nav1.7 antibody

Anti-Nav1.7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX134494
Anti-Nav1.7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX134494
Anti-Nav1.7 antibody used in Western Blot (WB). GTX134494
Anti-Nav1.7 antibody used in Western Blot (WB). GTX134494

Cat. No. GTX134494

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all Nav1.7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

226 kDa. ( Note )

Positive Control

mouse brain , rat brain

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.67 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of mouse Nav1.7. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2887296

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sodium channel, voltage-gated, type IX, alpha , Nav1.7 , PN1 , mKIAA4197

Cellular Localization

Cell membrane

Database

Research Area

DATA IMAGES

Anti-Nav1.7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX134494

GTX134494 ICC/IF Image

Nav1.7 antibody detects Nav1.7 protein at cell membrane by immunofluorescent analysis.
Sample: mouse dorsal root ganglia cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Nav1.7 stained by Nav1.7 antibody (GTX134494) diluted at 1:500.
Red: NF-H, a axon marker, stained by NF-H antibody [GT114] (GTX634289) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-Nav1.7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX134494

GTX134494 ICC/IF Image

Nav1.7 antibody detects Nav1.7 protein by immunofluorescent analysis.
Sample: DIV9 rat E18 primary cortical neuron cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: Nav1.7 stained by Nav1.7 antibody (GTX134494) diluted at 1:500.
Red: Tau, stained by Tau antibody [GT287] (GTX634809) diluted at 1:500.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-Nav1.7 antibody used in Western Blot (WB). GTX134494

GTX134494 WB Image

Mouse tissue extract (50 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Nav1.7 antibody (GTX134494) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Nav1.7 antibody used in Western Blot (WB). GTX134494

GTX134494 WB Image

Various tissue extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Nav1.7 antibody (GTX134494) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

REFERENCE

Application Reference

Ana M Moreno et al. Sci Transl Med 2021; 13 (584) Long-lasting analgesia via targeted in situ repression of NaV1.7 in mice.
Submit a Reference

REVIEW

There are currently no reviews for Nav1.7 antibody (GTX134494). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399
$ 169