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Nectin 1 antibody [R1.302] (PE)

Cat No. GTX00514-08

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 R1.302

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
100 test ($329)
See all Nectin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS 10 μl reagent / 100 μl of whole blood or 10⁶ cells in a suspension
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 15mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NIH/3T3 cells transfected with human CD111

Purification

Purified by size-exclusion chromatography

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD111,CLPED1,ED4,HIgR,HV1S,HVEC,NECTIN1,OFC7,PRR,PRR1,PVRL1,PVRR,PVRR1,SK12,nectin cell adhesion molecule 1,nectin1,Nectin 1

Cellular Localization

Cell membrane,Cell junction,Synapse,Presynaptic cell membrane,Secreted

Background

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 329