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Nectin 1 antibody [R1.302]

Anti-Nectin 1 antibody [R1.302] used in Flow cytometry (FACS). GTX00514

Cat. No. GTX00514

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 R1.302

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, IP, IHC

Reactivity

 Human
Package
100 μg ($399)
See all Nectin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

NIH/3T3 cells transfected with human CD111

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD111 , CLPED1 , ED4 , HIgR , HV1S , HVEC , NECTIN1 , OFC7 , PRR , PRR1 , PVRL1 , PVRR , PVRR1 , SK12 , nectin cell adhesion molecule 1 , nectin1 , Nectin 1

Cellular Localization

Cell membrane,Cell junction,Synapse,Presynaptic cell membrane,Secreted

Background

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]

Database

Research Area

DATA IMAGES

Anti-Nectin 1 antibody [R1.302] used in Flow cytometry (FACS). GTX00514

GTX00514 FACS Image

FACS analysis of human peripheral blood using GTX00514 Nectin 1 antibody [R1.302].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399