GeneTex
United States (US)

Neuregulin-1 antibody

GTX31173_IHC-P_18121410_399.jpg

Cat No. GTX31173

Host Rabbit
Clonality Polyclonal
Application WB, IHC-P, ELISA, Neut
Reactivity Human
APPLICATION

Calculated MW

70 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, pH 7.2

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant Human Heregulinβ-1

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Neuregulin 1,Aria,Ggf,Ggf2,Hgl,Hrg,Hrg1,Hrga,Mst131,Mstp131,Ndf,Nrg1-It2,Smdf,Nrg1

Background

The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure, and thereby these isoforms are classified into types I, II, III, IV, V and VI. The gene dysregulation has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD). [provided by RefSeq, May 2009]

Database

Research Area

DATA IMAGES
GTX31173_IHC-P_18121410_399.jpg

GTX31173 IHC-P Image

IHC-P analysis of human normal breast tissue using Neuregulin-1 antibody. An HRP-labeled polymer detection system was used with a DAB chromogen. Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended.

Package List Price ($)
$ 319