*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
HRGbeta1 recombinant protein, LS174T cells
Reacts weakly with alpha-HRG and strongly with beta-HRG. Does not inhibit the binding of HRG to ErbB receptors but it efficiently blocks the HRG-induced proliferation and differentiation of cultured human mammary cells.
Buffer without any additives.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
A highly antigenic synthetic peptide from the EGF-like domain of human heregulin
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Apr 2016]
GTX82945 WB Image
Western blot analysis of Heregulin using GTX82945