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Neurokinin 1 Receptor antibody

Anti-Neurokinin 1 Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX30183
Anti-Neurokinin 1 Receptor antibody used in Western Blot (WB). GTX30183
Anti-Neurokinin 1 Receptor antibody used in Western Blot (WB). GTX30183

Cat. No. GTX30183

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human, Mouse, Rat, Guinea pig, Monkey
Package
100 μl ($439)
See all Neurokinin 1 Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/ml
IHC-P 10 μg/ml
FACS 1:10 - 1:1000
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A peptide derived from the N-terminus region between amino acids 1-50 of human Neurokinin 1 Receptor [UniProt# P25103]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

tachykinin receptor 1 , NK1R , NKIR , SPR , TAC1R

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-Neurokinin 1 Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX30183

GTX30183 IHC-P Image

IHC-P analysis of human brain tissue using GTX30183 Neurokinin 1 Receptor antibody.

Anti-Neurokinin 1 Receptor antibody used in Western Blot (WB). GTX30183

GTX30183 WB Image

WB analysis of human, mouse, rat brain tissue lysate using GTX30183 Neurokinin 1 Receptor antibody.
Dilution : 2 μg/ml

Anti-Neurokinin 1 Receptor antibody used in Western Blot (WB). GTX30183

GTX30183 WB Image

WB analysis of (1) human, (2) rat, and (3) monkey brain lysate using GTX30183 Neurokinin 1 Receptor antibody.

REFERENCE

Clone Reference

Shrikhande SV et al. Pain 2001; 91 (3):209-17 NK-1 receptor gene expression is related to pain in chronic pancreatitis.
Tooney PA et al. Biol Psychiatry 2001; 49 (6):523-7 Increased tachykinin NK(1) receptor immunoreactivity in the prefrontal cortex in schizophrenia.
Tooney PA et al. Neurosci Lett 2000; 283 (3):185-8 Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 439