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Neuropeptide Y antibody [8]

Anti-Neuropeptide Y antibody [8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60971
Anti-Neuropeptide Y antibody [8] used in IHC (Paraffin sections) (IHC-P). GTX60971
Anti-Neuropeptide Y antibody [8] used in IHC (Paraffin sections) (IHC-P). GTX60971
Anti-Neuropeptide Y antibody [8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60971
Anti-Neuropeptide Y antibody [8] used in IHC (Paraffin sections) (IHC-P). GTX60971

Cat. No. GTX60971

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8

Isotype

 IgG1

Application

 ICC/IF, IHC-P, IHC-Fr, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μl ($519)
See all Neuropeptide Y products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Product Note

This antibody binds full length human/rat Neuropeptide Y (NPY). Cross-reactivity with NPY (1-24) , NPY (18-36), PYY or PP was <0.2%.

PROPERTIES

Form

Liquid

Buffer

0.01M Phosphate buffer, 0.5M NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic human/rat neuropeptide Y

Purification

Protein-A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

neuropeptide Y , PYY4

Cellular Localization

Secreted

Background

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

Database

Research Area

DATA IMAGES

Anti-Neuropeptide Y antibody [8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60971

GTX60971 ICC/IF Image

GTX60971 tested on tissue from human cerebral cortex, applying ultra thin sections using a technique called array tomography. (antibody: green, DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil. Courtesy of Dr. Nancy O'Rourke, Stanford University.

Anti-Neuropeptide Y antibody [8] used in IHC (Paraffin sections) (IHC-P). GTX60971

GTX60971 IHC-P Image

Paraffin embedded mouse brain tissue (fibres in the hilus of the hippocampus) from a mouse suffering an epiletic attack just before perfusion stained with GTX60971 diluted 1/1000

Anti-Neuropeptide Y antibody [8] used in IHC (Paraffin sections) (IHC-P). GTX60971

GTX60971 IHC-P Image

Enlarged section of a paraffin embedded mouse brain tissue (fibres in the hilus of the hippocampus) from a mouse suffering an epileptic attack just before perfusion stained with GTX60971 diluted 1/1000

Anti-Neuropeptide Y antibody [8] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60971

GTX60971 ICC/IF Image

GTX60971 tested on tissue from human cerebral cortex, applying ultra thin sections using a technique called array tomography. (antibody: green, DAPI-stained nuclei: blue). The antibody labels NPY-positive processes in the neutrophil. Courtesy of Dr. Nancy O'Rourke, Stanford University.

Anti-Neuropeptide Y antibody [8] used in IHC (Paraffin sections) (IHC-P). GTX60971

GTX60971 IHC-P Image

Paraffin embedded mouse brain tissue (interneurons in the cortex) stained with GTX60971 diluted 1/1000

REFERENCE

Application Reference

Nakanishi S et al. J Vet Med Sci 2023; 85 (2) : 123-134 Histological study on regional specificity of the mucosal nerve network in the rat large intestine.
Application : IHC-Fr
Reactivity : Rat
Dongxiao Zhang et al. Front Endocrinol (Lausanne) 2021; 12 : 727915 Upregulation of Mir342 in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control.
Application : IHC-Fr
Reactivity : Mouse
Submit a Reference

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 519