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Neuroserpin antibody, C-term

Anti-Neuroserpin antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89544
Anti-Neuroserpin antibody, C-term used in Western Blot (WB). GTX89544

Cat No. GTX89544

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89544-PEP).

Predict Reactivity

Mouse, Rat, Bovine, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-TMNTSGHDFEEL, from the C Terminus of the protein sequence according to NP_005016.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

serpin family I member 1 , PI12 , neuroserpin

Cellular Localization

Secreted

Background

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Neuroserpin antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89544

GTX89544 IHC-P Image

IHC-P analysis of human cortex tissue section using GTX89544 Neuroserpin antibody, C-term.
Antigen retrieval : citrate buffer (pH 6.0)
Dilution : 5 μg/ml

Anti-Neuroserpin antibody, C-term used in Western Blot (WB). GTX89544

GTX89544 WB Image

WB analysis of human brain lysate using GTX89544 Neuroserpin antibody, C-term.
Dilution : 1μg/ml
Loading : 35μg protein in RIPA buffer

REFERENCE

There are currently no references for Neuroserpin antibody, C-term (GTX89544). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Neuroserpin antibody, C-term (GTX89544). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf