APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1:500-2000 |
| 1:400-800 |
| Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
0.01M TBS pH7.4, 0.5% BSA, 25% Glycerol
Preservative
0.015% ProClin 300
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide derived between 13820 amino acids of human Nociceptin Receptor
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
opioid related nociceptin receptor 1 , KOR-3 , NOCIR , NOP , NOPr , OOR , ORL1
Cellular Localization
Cell membrane; Multi-pass membrane protein,Cytoplasmic vesicle
Background
The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
Database
Research Area
DATA IMAGES
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GTX37594 WB Image
WB analysis of rat heart (Lane 1) and rat brain(Lane 2) tissue lysates using GTX37594 Nociceptin Receptor antibody.
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GTX37594 IHC-P Image
IHC-P analysis of rat brain tissue using GTX37594 Nociceptin Receptor antibody.
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GTX37594 IHC-Fr Image
IHC-Fr analysis of mouse hippocampus tissue using GTX37594 Nociceptin Receptor antibody.
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GTX37594 IHC-Fr Image
IHC-Fr analysis of human placenta tissue using GTX37594 Nociceptin Receptor antibody.
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REFERENCE
There are currently no references for Nociceptin Receptor antibody (GTX37594). Be the first to share your publications with this product.
REVIEW
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