GeneTex
United States (US)

Nociceptin Receptor antibody

GTX37594_20190129_WB_19012901_274.jpg
GTX37594_20190129_IHC-P_19012901_990.jpg
GTX37594_20190129_IHC-Fr_1_19012901_701.jpg
GTX37594_20190129_IHC-Fr_19012901_639.jpg

Cat No. GTX37594

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-Fr
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-2000
IHC-P 1:400-800
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 13820 amino acids of human Nociceptin Receptor

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

KOR-3,NOCIR,NOP,NOPr,OOR,ORL1

Cellular Localization

Cell membrane,Cytoplasmic vesicle

Background

The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Database

Research Area

DATA IMAGES
GTX37594_20190129_WB_19012901_274.jpg

GTX37594 WB Image

WB analysis of rat heart (Lane 1) and rat brain(Lane 2) tissue lysates using GTX37594 Nociceptin Receptor antibody.

GTX37594_20190129_IHC-P_19012901_990.jpg

GTX37594 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37594 Nociceptin Receptor antibody.

GTX37594_20190129_IHC-Fr_1_19012901_701.jpg

GTX37594 IHC-Fr Image

IHC-Fr analysis of mouse hippocampus tissue using GTX37594 Nociceptin Receptor antibody.

GTX37594_20190129_IHC-Fr_19012901_639.jpg

GTX37594 IHC-Fr Image

IHC-Fr analysis of human placenta tissue using GTX37594 Nociceptin Receptor antibody.

Package List Price ($)
$ 319