GeneTex
United States (US)

Nociceptin Receptor antibody

GTX37594_20190129_WB_19012901_274.jpg
GTX37594_20190129_IHC-P_19012901_990.jpg
GTX37594_20190129_IHC-Fr_1_19012901_701.jpg
GTX37594_20190129_IHC-Fr_19012901_639.jpg

Cat No. GTX37594

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, IHC-Fr
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-2000
IHC-P 1:400-800
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

41 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.01M TBS pH7.4, 0.5% BSA, 0.015% ProClin™ 300, 25% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 13820 amino acids of human Nociceptin Receptor

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Opioid Related Nociceptin Receptor 1,Kor-3,Nocir,Nop,Nopr,Oor,Orl1,Oprl1

Cellular Localization

Cell membrane,Cytoplasmic vesicle

Background

The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between this gene and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Database

Research Area

DATA IMAGES
GTX37594_20190129_WB_19012901_274.jpg

GTX37594 WB Image

WB analysis of rat heart (Lane 1) and rat brain(Lane 2) tissue lysates using GTX37594 Nociceptin Receptor antibody.

GTX37594_20190129_IHC-P_19012901_990.jpg

GTX37594 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37594 Nociceptin Receptor antibody.

GTX37594_20190129_IHC-Fr_1_19012901_701.jpg

GTX37594 IHC-Fr Image

IHC-Fr analysis of mouse hippocampus tissue using GTX37594 Nociceptin Receptor antibody.

GTX37594_20190129_IHC-Fr_19012901_639.jpg

GTX37594 IHC-Fr Image

IHC-Fr analysis of human placenta tissue using GTX37594 Nociceptin Receptor antibody.

Package List Price ($)
$ 319