GeneTex
United States (US)

OATP2 antibody [ESL]

Cat No. GTX15441

Host Mouse
Clonality Monoclonal
Clone Name ESL
Isotype IgM
Application WB, ICC/IF, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ICC/IF 1:100
IP Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Specificity/Sensitivity

This antibody shows no cross-reactivity to other OATP isoforms.
PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant, 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to residues E(671) S L N K N K H F V P S A G A D S E T H C(691) of human OATP2.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Solute Carrier Organic Anion Transporter Family Member 1B1,Hblrr,Lst-1,Lst1,Oatp-C,Oatp1B1,Oatp2,Oatpc,Slc21A6,Slco1B1

Cellular Localization

Basolateral cell membrane

Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Database

Package List Price ($)
$ 319