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OATP2 antibody

Anti-OATP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31621
Anti-OATP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31621
Anti-OATP2 antibody used in Western Blot (WB). GTX31621

Cat. No. GTX31621

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all OATP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
ICC/IF Assay dependent
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

Human Liver Tissue Slide , Human Liver Tissue Lysate

Product Note

This antibody is human specific. At least four isoforms are known to exist. This antibody is predicted to not cross-react with other SLCO1B proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

OATP2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human OATP2.The immunogen is located within the last 50 amino acids of OATP2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887622

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

solute carrier organic anion transporter family member 1B1 , HBLRR , LST-1 , LST1 , OATP-C , OATP1B1 , OATP2 , OATPC , SLC21A6

Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Database

Research Area

DATA IMAGES

Anti-OATP2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31621

GTX31621 IHC-P Image

IHC-P analysis of human liver tissue using GTX31621 OATP2 antibody.
Working concentration : 20 μg/ml

Anti-OATP2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31621

GTX31621 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX31621 OATP2 antibody.
Working concentration : 2.5 μg/ml

Anti-OATP2 antibody used in Western Blot (WB). GTX31621

GTX31621 WB Image

WB analysis of human liver tissue lysate using GTX31621 OATP2 antibody.
Working concentration : 1 μg/ml

REFERENCE

Application Reference

Lu CC et al. In Vivo 2018; 32 (3) : 677-684 cDNA Microarray Analysis and Influx Transporter OATP1B1 in Liver Cells After Exposure to * Disodium, a Gadolinium-based Contrast Agent in MRI Liver Imaging.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399