GeneTex
United States (US)

OATP2 antibody

GTX31621_2806_WB_20180221_18121410_873.jpg
GTX31621_1291_IHC-P_20180221_18121410_370.jpg
GTX31621_227_ICC-IF_20180221_18121410_483.jpg

Cat No. GTX31621

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF Assay dependent
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Positive Control

Human Liver Tissue Slide , Human Liver Tissue Lysate

Specificity/Sensitivity

This antibody is human specific. At least four isoforms are known to exist. This antibody is predicted to not cross-react with other SLCO1B proteins.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

OATP2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human OATP2.The immunogen is located within the last 50 amino acids of OATP2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Solute Carrier Organic Anion Transporter Family Member 1B1,Hblrr,Lst-1,Lst1,Oatp-C,Oatp1B1,Oatp2,Oatpc,Slc21A6,Slco1B1

Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009]

Database

DATA IMAGES
GTX31621_2806_WB_20180221_18121410_873.jpg

GTX31621 WB Image

WB analysis of human liver tissue lysate using GTX31621 OATP2 antibody.
Working concentration : 1 μg/ml

GTX31621_1291_IHC-P_20180221_18121410_370.jpg

GTX31621 IHC-P Image

IHC-P analysis of human liver tissue using GTX31621 OATP2 antibody.
Working concentration : 20 μg/ml

GTX31621_227_ICC-IF_20180221_18121410_483.jpg

GTX31621 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX31621 OATP2 antibody.
Working concentration : 2.5 μg/ml

REFERENCE
Package List Price ($)
$ 339