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United States (US)

OATP8 blocking peptide

Cat. No. GTX88295-PEP

Species

 Human
Package
100 μg ($239)

APPLICATION

Product Note

The peptide was used in the production of GTX88295.

PROPERTIES

Form

Lyophilized powder

Buffer

Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

C-NGTSPEIVEKD

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Solute Carrier Organic Anion Transporter Family Member 1B3 , Hblrr , Lst-2 , Lst-3Tm13 , Lst3 , Oatp-8 , Oatp1B3 , Oatp8 , Slc21A8 , Slco1B3

Background

This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. [provided by RefSeq, Feb 2012]

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 239