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OAZ1 antibody, N-term

Anti-OAZ1 antibody, N-term used in Western Blot (WB). GTX81427
Anti-OAZ1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81427

Cat No. GTX81427

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
400 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 2-31 amino acids from the N-terminal region of human OAZ1.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ornithine decarboxylase antizyme 1 , AZ1 , AZI , OAZ

Background

The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 1, the first member of the antizyme family, that has broad tissue distribution, and negatively regulates intracellular polyamine levels by binding to and targeting ODC for degradation, as well as inhibiting polyamine uptake. Antizyme 1 mRNA contains two potential in-frame AUGs; and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization. Alternatively spliced transcript variants have also been noted for this gene. [provided by RefSeq, Dec 2014]

Database

Research Area

DATA IMAGES

Anti-OAZ1 antibody, N-term used in Western Blot (WB). GTX81427

GTX81427 WB Image

WB analysis of mouse heart tissue lysate (35ug/lane) using GTX81427 OAZ1 antibody, N-term.

Anti-OAZ1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81427

GTX81427 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX81427 OAZ1 antibody, N-term.

REFERENCE

There are currently no references for OAZ1 antibody, N-term (GTX81427). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf