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GeneTex
United States (US)

OAZ1 antibody

OAZ1-antibody-GTX87664-IHC-1_18121411_340.jpg

Cat No. GTX87664

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human, Mouse, Rat
See all OAZ1 products
APPLICATION

Application Note

We recommend the following starting dilutions:

IHC: 1:50~1:100
ELISA: 1:40000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

25 kDa. ( Note )

Specificity/Sensitivity

OAZ1 Antibody detects endogenous levels of total OAZ1 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human OAZ1.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Ornithine Decarboxylase Antizyme 1,Az1,Azi,Oaz,Oaz1

Background

Binds to, and destabilizes, ornithine decarboxylase which is then degraded. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1.

Database

Research Area

DATA IMAGES
OAZ1-antibody-GTX87664-IHC-1_18121411_340.jpg

GTX87664 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using OAZ1 Antibody. The picture on the right is treated with the synthesized peptide.
Package List Price ($)
$ 339