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OLIG2 antibody

Anti-OLIG2 antibody used in Western Blot (WB). GTX31569

Cat. No. GTX31569

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all OLIG2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

Positive Control

EL4 Cell Lysate(GTX27183)

Product Note

It is predicted to not cross-react with other members of the OLIG family of proteins. At least three isoforms of OLIG2 are known to exist; this antibody will detect all three isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

OLIG2 antibody was raised against a 15 amino acid peptide near the amino terminus of human OLIG2.The immunogen is located within amino acids 80 - 130 of OLIG2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887620

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

oligodendrocyte transcription factor 2 , BHLHB1 , OLIGO2 , PRKCBP2 , RACK17 , bHLHe19

Cellular Localization

Nucleus,Cytoplasm

Background

This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-OLIG2 antibody used in Western Blot (WB). GTX31569

GTX31569 WB Image

WB analysis of EL4 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX31569 OLIG2 antibody.
Working concentration : 1 μg/ml

REFERENCE

Application Reference

Tosuner Z et al. Oncol Lett 2018; 16 (2) : 2402-2408 BRAF V600E mutation and BRAF VE1 immunoexpression profiles in different types of glioblastoma.
Zeynep Tosuner et al. Oncology Letters 2018; (Epub) BRAF V600E mutation and BRAF VE1 immunoexpression profiles in different types of glioblastoma.
Application : IHC-P
Reactivity : Human
Rissi DR et al. J Vet Diagn Invest 2015; 27 (3) : 396-400 Cerebral oligodendroglioma mimicking intraventricular neoplasia in three dogs.
Application : IHC-P
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399