*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Human Recombinant sLOX-158-273
PBS pH 7.4, 0.09% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
6.90 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant sLOX-1 expressed in E. coli.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Oxidized Low Density Lipoprotein Receptor 1,Clec8A,Lox1,Loxin,Scare1,Slox1,Olr1
A secreted form also exists.
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]