GeneTex
United States (US)

OLR1 / LOX-1 antibody [B017M]

Cat No. GTX39126

Host Mouse
Clonality Monoclonal
Clone Name B017M
Isotype IgG1
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Specificity/Sensitivity

Human Recombinant sLOX-158-273
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

6.90 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant sLOX-1 expressed in E. coli.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Oxidized Low Density Lipoprotein Receptor 1,Clec8A,Lox1,Loxin,Scare1,Slox1,Olr1

Cellular Localization

A secreted form also exists.

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Database

Research Area

Package List Price ($)
$ 289