GeneTex
United States (US)

OLR1 / LOX-1 antibody

GTX39812_4510_IHC-Fr_18121410_873.jpg
GTX39812_4509_IHC-Fr_18121410_251.jpg
GTX39812_4507_FACS_18121410_281.jpg

Cat No. GTX39812

Host Sheep
Clonality Polyclonal
Isotype IgG
Application WB, IHC-Fr, FACS, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1/10-1/100
IHC-Fr Assay dependent
FACS 1/10
IP Assay dependent

Note :

Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

31 kDa kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes the type II membrane glycoprotein LOX-1 (lectin-like oxidized LDL receptor-1).
PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide, 1% BSA

Concentration

0.1mg/ml

Antigen Species

Human

Immunogen

Recombinant human extracellular domain LOX-1 protein from bacteria.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

OLR1 Antibody , SCARE1 Antibody , LOX1 Antibody , SLOX1 Antibody , CLEC8A Antibody , LOXIN Antibody

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
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Database

Research Area

DATA IMAGES
GTX39812_4510_IHC-Fr_18121410_873.jpg

GTX39812 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX39812 OLR1 / LOX-1 antibody.

GTX39812_4509_IHC-Fr_18121410_251.jpg

GTX39812 IHC-Fr Image

IHC-Fr analysis of human tonsil tissue using GTX39812 OLR1 / LOX-1 antibody.

GTX39812_4507_FACS_18121410_281.jpg

GTX39812 FACS Image

FACS analysis of HUVEC cells using GTX39812 OLR1 / LOX-1 antibody.