GeneTex
United States (US)

OLR1 / LOX-1 antibody

Cat No. GTX39817

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 1/100-1/200
ELISA Assay dependent

Note :

Fixation with 4% paraformaldehyde or methanol is recommended.
Not tested in other applications.

Calculated MW

31 kDa kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Serum, 0.09% Sodium Azide

Antigen Species

Human

Immunogen

Peptide corresponding to the C-terminal (extracellular) region of human LOX-1.

Purification

Serum

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

OLR1 Antibody , SCARE1 Antibody , LOX1 Antibody , SLOX1 Antibody , CLEC8A Antibody , LOXIN Antibody

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
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Database

Research Area

Reference