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OLR1 / LOX-1 antibody

Anti-OLR1 / LOX-1 antibody used in Western Blot (WB). GTX59636

Cat No. GTX59636

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC

Reactivity

Human, Mouse, Rat
Package
100 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-4 μg/ml
IHC Assay dependent
Not tested in other applications.

Calculated MW

30.96 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.2, 30% glycerol, 0.5% BSA, 0.03% ProClin

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide near the N-terminus of human Lox-1

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_10726212

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CLEC8A , LOX1 , LOXIN , OLR1 , SCARE1 , SLOX1 , oxidized low density lipoprotein receptor 1 , LOX-1

Cellular Localization

Cell membrane,Cell membrane,Membrane raft,Secreted

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Database

Research Area

DATA IMAGES

Anti-OLR1 / LOX-1 antibody used in Western Blot (WB). GTX59636

GTX59636 WB Image

WB analysis of Jurkat cell lysate using GTX59636 OLR1 / LOX-1 antibody.

REFERENCE

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf