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OLR1 / LOX-1 antibody

Anti-OLR1 / LOX-1 antibody used in Western Blot (WB). GTX59636

Cat No. GTX59636

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC

Reactivity

Human, Mouse, Rat
Package
100 μg ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-4 μg/ml
IHC Assay dependent
Not tested in other applications.

Calculated MW

30.96 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.2, 30% glycerol, 0.5% BSA, 0.03% ProClin

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide near the N-terminus of human Lox-1

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CLEC8A , LOX1 , LOXIN , OLR1 , SCARE1 , SLOX1 , oxidized low density lipoprotein receptor 1 , LOX-1

Cellular Localization

Cell membrane,Cell membrane,Membrane raft,Secreted

Background

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

Database

Research Area

DATA IMAGES

Anti-OLR1 / LOX-1 antibody used in Western Blot (WB). GTX59636

GTX59636 WB Image

WB analysis of Jurkat cell lysate using GTX59636 OLR1 / LOX-1 antibody.

REFERENCE

REVIEW

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Package List Price ($)
$ 379