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OPG antibody [5A11]

Anti-OPG antibody [5A11] used in Western Blot (WB). GTX80404
Anti-OPG antibody [5A11] used in IHC (Paraffin sections) (IHC-P). GTX80404

Cat. No. GTX80404

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5A11

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all OPG products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member11b , OCIF , OPG , PDB5 , TNFRSF11B , TR1 , Osteoprotegerin , osteoclastogenesis inhibitory factor

Cellular Localization

Secreted

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]

Database

  • Gene ID: 4982 TNFRSF11B
  • UniProt: O00300 TNFRSF11B

Research Area

DATA IMAGES

Anti-OPG antibody [5A11] used in Western Blot (WB). GTX80404

GTX80404 WB Image

WB analysis of HEK293 (1) and OPG (AA: 22-401)-hIgGFc transfected HEK293 (2) cell lysate using GTX80404 OPG antibody [5A11].

Anti-OPG antibody [5A11] used in IHC (Paraffin sections) (IHC-P). GTX80404

GTX80404 IHC-P Image

IHC-P analysis of mammary cancer tissue (left) and lung cancer tissue (right) using GTX80404 OPG antibody [5A11].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399