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OPG antibody (Biotin)

Anti-OPG antibody (Biotin) used in ELISA (ELISA). GTX18068
Anti-OPG antibody (Biotin) used in ELISA (ELISA). GTX18068

Cat. No. GTX18068

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA, Sandwich ELISA

Reactivity

 Human
Package
25 μg ($399)
See all OPG products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1 - 0.2 μg/mL
ELISA 0.15 - 0.30 μg/mL
Sandwich ELISA 0.25 - 1.0 ug/ml

Note :

Sandwich ELISA
Capture : Anti-Human OPG antibody, Detection : GTX18068
Not tested in other applications.

Calculated MW

46 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hOPG (human OPG).

Purification

Purified by affinity chromatography

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member11b , OCIF , OPG , PDB5 , TNFRSF11B , TR1 , Osteoprotegerin , osteoclastogenesis inhibitory factor

Cellular Localization

Secreted

Background

Osteoprotegerin (OPG) belongs to the TNF receptor (TNFR) family. Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.

Database

  • Gene ID: 4982 TNFRSF11B
  • UniProt: O00300 TNFRSF11B

Research Area

DATA IMAGES

Anti-OPG antibody (Biotin) used in ELISA (ELISA). GTX18068

GTX18068 ELISA Image

ELISA analysis of human OPG recombinant protein (0.2 – 0.4 ng/well) using GTX18068 OPG antibody (Biotin).
Working concentration : 0.25- 1.0 ug/ml

Anti-OPG antibody (Biotin) used in ELISA (ELISA). GTX18068

GTX18068 ELISA Image

ELISA analysis of human OPG recombinant protein(0.2 - 0.4 ng/well) using GTX18068 OPG antibody (Biotin)(detection antibody) at 0.25- 1.0 ug/ml and Anti-Human OPG as a capture antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399