GeneTex
United States (US)

OTUD5 antibody

Anti-OTUD5 antibody used in IHC (Paraffin sections) (IHC-P). GTX31361
Anti-OTUD5 antibody used in Western Blot (WB). GTX31361
Anti-OTUD5 antibody used in IHC (Paraffin sections) (IHC-P). GTX31361

Cat No. GTX31361

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

61 kDa. ( Note )

Positive Control

Human Kidney Tissue Lysate(GTX29995)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

OTUD5 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of the human OTUD5.The immunogen is located within amino acids 400 - 450 of OTUD5.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Otu Deubiquitinase 5,Duba,Otud5

Background

This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]

Database

DATA IMAGES
Anti-OTUD5 antibody used in IHC (Paraffin sections) (IHC-P). GTX31361

GTX31361 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31361 OTUD5 antibody.
Working concentration : 20 μg/ml

Anti-OTUD5 antibody used in Western Blot (WB). GTX31361

GTX31361 WB Image

WB analysis of human kidney tissue lysate using GTX31361 OTUD5 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-OTUD5 antibody used in IHC (Paraffin sections) (IHC-P). GTX31361

GTX31361 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX31361 OTUD5 antibody.
Working concentration : 2.5 μg/ml

Package List Price ($)
$ 339