APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 0.2-2.5 ug/ml |
| 2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
HeLa , HepG2 , Jurkat , MCF-7
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human OTX2
Purification
Affinity Purified
Conjugation
Unconjugated
RRID
AB_424828
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
orthodenticle homeobox 2 , CPHD6 , MCOPS5
Cellular Localization
Nucleus
Background
This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
Database
Research Area
DATA IMAGES
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GTX77880 IHC-P Image
IHC-P analysis of human heart tissue using GTX77880 OTX2 antibody at 4.0-8.0μg/ml.
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GTX77880 WB Image
WB analysis of HepG2 cells using GTX77880 OTX2 antibody at 1μg/ml.
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GTX77880 WB Image
WB analysis of Jurkat cells using GTX77880 OTX2 antibody at 1μg/ml.
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GTX77880 WB Image
WB analysis of HeLa cells using GTX77880 OTX2 antibody at 1μg/ml.
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GTX77880 WB Image
WB analysis of Jurkat cells using GTX77880 OTX2 antibody at 0.2-1μg/ml.
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GTX77880 WB Image
WB analysis of MCF-7 cells using GTX77880 OTX2 antibody at 1μg/ml.
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GTX77880 IHC-P Image
IHC-P analysis of human stomach tissue using GTX77880 OTX2 antibody at 4.0-8.0μg/ml.
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REFERENCE
There are currently no references for OTX2 antibody, N-term (GTX77880). Be the first to share your publications with this product.
REVIEW
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