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Oct4 antibody [N1NK]

Anti-Oct4 antibody [N1NK] used in IHC (Paraffin sections) (IHC-P). GTX01931

Cat. No. GTX01931

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 N1NK

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($479)
See all Oct4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to 147 amino acids of the N-terminus of the human Oct-3/4 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

POU class 5 homeobox 1 , OCT3 , OCT4 , OTF-3 , OTF3 , OTF4 , Oct-3 , Oct-4

Cellular Localization

Cytoplasm , Nucleus

Background

This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Oct 2013]

Database

Research Area

DATA IMAGES

Anti-Oct4 antibody [N1NK] used in IHC (Paraffin sections) (IHC-P). GTX01931

GTX01931 IHC-P Image

IHC-P analysis of human testes, seminoma tissue using GTX01931 Oct4 antibody [N1NK]. Note nuclear staining of neoplastic cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 479