Osteocalcin antibody

Cat. No. GTX04704

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, IHC-P
Reactivity	Human
Package	400 μl ($399)

See all Osteocalcin products

Datasheet

View product citations for antibody GTX04704 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:2000
IHC-P	1:50-1:100

Not tested in other applications.

Calculated MW

11 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human Osteocalcin.

Purification

Purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BGLAP,BGP,OC,OCN,bone gammacarboxyglutamate protein,Osteocalcin,bone gamma-carboxyglutamate protein

Cellular Localization

Secreted

Background

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015]

Database

Gene ID: 632 BGLAP
UniProt: P02818 BGLAP

Research Area

DATA IMAGES

GTX04704 IHC-P Image

IHC-P analysis of human hepatocarcinoma tissue using GTX04704 Osteocalcin antibody.

GTX04704 WB Image

WB analysis of MG-63 whole cell lysate using GTX04704 Osteocalcin antibody.
Loading : 20 μg
Dilution : 1:2000

REFERENCE

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REVIEW

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Package

List Price ($)

400 μl

$ 399

Qty