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Oxytocin antibody, C-term

Anti-Oxytocin antibody, C-term used in IHC (Frozen sections) (IHC-Fr). GTX88457

Cat No. GTX88457

Host Goat
Clonality Polyclonal
Isotype IgG
Application IHC-Fr
Reactivity Human
Package
100 μg ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr 0.05-0.15μg/ml

Note :

IHC-Fr
Human Hypothalamus shows staining of magnocellular oxytocin neurons in the supraoptic nucleus.

Not tested in other applications.

Calculated MW

13 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88457-PEP).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence HADPACDAEATFSQR, from the C Terminus of the protein sequence according to NP_000906.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Oxytocin/Neurophysin I Prepropeptide,Ot,Ot-Npi,Oxt-Npi,Oxt

Background

This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]

Database

DATA IMAGES
Anti-Oxytocin antibody, C-term used in IHC (Frozen sections) (IHC-Fr). GTX88457

GTX88457 IHC-Fr Image

IHC-Fr analysis of PFA-perfused human hypothalamus using GTX88457 Oxytocin antibody, C-term.
Antigen retrieval : citrate buffer pH 6 at 80C for 30min
Dilution : 0.05µg/ml

REFERENCE
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REVIEW
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Package List Price ($)
$ 329