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P-Cadherin antibody [9V11]

Anti-P-Cadherin antibody [9V11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX52961

Cat. No. GTX52961

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 9V11

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-Fr, FACS

Reactivity

 Human
Package
100 μg ($399)
See all P-Cadherin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
ICC/IF Assay dependent
IHC-Fr 1:50 - 1:200
FACS 1:50 - 1:200
Not tested in other applications.

Calculated MW

91 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant P-Cadherin EC domain

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CDH3 , CDHP , HJMD , PCAD , cadherin 3 , P-Cadherin , Cadherin 3

Cellular Localization

Cell membrane

Background

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-P-Cadherin antibody [9V11] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX52961

GTX52961 ICC/IF Image

ICC/IF analysis of human trophoblasts using GTX52961 P-Cadherin antibody [9V11].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399