APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
5-10 μg/ml |
5-10 μg/ml |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
This antibody inhibits P- Cadherin dependent cell-cell contact.
PROPERTIES
Form
Liquid
Buffer
10mM PBS pH7.4, 1% BSA
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human epidermal carcinoma cell line A431.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CDH3 , CDHP , HJMD , PCAD , cadherin 3 , P-Cadherin , Cadherin 3
Cellular Localization
Cell membrane
Background
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
Database
Research Area
REFERENCE
There are currently no references for P-Cadherin antibody [NCC-CAD-299] (GTX12222). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for P-Cadherin antibody [NCC-CAD-299] (GTX12222). Be the first to share your experience with this product.