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P2X2 antibody

Anti-P2X2 antibody used in Western Blot (WB). GTX10262

Cat No. GTX10262

Host Guinea pig
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-Fr
Reactivity Human, Mouse, Rat, Guinea pig, Pig
Package
50 μl ($319)
APPLICATION

Application Note

ICC: Use at a dilution of 1/500. IHC-Fr: Use at a dilution of 1/500. WB: Use at a dilution of 1/500. Predicted molecular weight: 47.8 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

53 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.05% Sodium Azide; Constituents: Whole Serum

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Rat

Immunogen

Synthetic peptide: DSTSTDPKGLAQL, corresponding to amino acids 460-472 of Rat P2X2.

Purification

Whole antiserum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Purinergic Receptor P2X 2 , P2X2 , P2Rx2

Cellular Localization

Plasma membrane

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.

Database

Research Area

DATA IMAGES
Anti-P2X2 antibody used in Western Blot (WB). GTX10262

GTX10262 WB Image

Western blot analysis indicated that concatamerized trimers remain intact. Total protein from oocytes injected with RNA for wild type P2X2 monomer, or trimer HH-HH-HH, HA-AA-AH, and AA-AA-HH was separated by SDS-PAGE under reducing conditions on a 4–12% gradient gel along with protein from uninjected

REFERENCE
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Package List Price ($)
$ 319