GeneTex
United States (US)

P2X7 antibody

GTX31600_224_ICC-IF_20180221_18121410_881.jpg
GTX31600_223_ICC-IF_20180221_18121410_348.jpg
GTX31600_2785_WB_20180221_18121410_990.jpg

Cat No. GTX31600

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Positive Control

3T3 Cell Lysate , 3T3/BALB Cell Slide
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

P2RX7 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human P2RX7.The immunogen is located within the last 50 amino acids of P2RX7.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Purinergic Receptor P2X 7,P2X7,P2Rx7

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]

Research Area

DATA IMAGES
GTX31600_224_ICC-IF_20180221_18121410_881.jpg

GTX31600 ICC/IF Image

ICC/IF analysis of 3T3 cells using GTX31600 P2X7 antibody.
Working concentration : 20 μg/ml

GTX31600_223_ICC-IF_20180221_18121410_348.jpg

GTX31600 ICC/IF Image

ICC/IF analysis of 3T3 cells using GTX31600 P2X7 antibody.
Working concentration : 5 μg/ml

GTX31600_2785_WB_20180221_18121410_990.jpg

GTX31600 WB Image

WB analysis of 3T3 cell lysate using GTX31600 P2X7 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Package List Price ($)
$ 329