GeneTex
United States (US)

P2Y1 antibody

GTX16924_ICCIF_18121410_766.jpg
GTX16924_FACS_18121410_199.jpg
GTX16924_WB_18121410_679.jpg
GTX16924_IHC_18121410_166.jpg

Cat No. GTX16924

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, FACS, IHC
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

42 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide SDEYLRSYFIYSMC, corresponding to amino acid residues 207-220 of human P2Y1 Receptor (Accession P47900 ). 2nd extracellular loop.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Purinergic Receptor P2Y1,P2Y1,Sarcc,P2Ry1

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16924_ICCIF_18121410_766.jpg

GTX16924 ICC/IF Image

Anti-P2Y1_Receptor_(extracellular) - Expression of P2Y1 receptor in rat PC12 cells Immunocytochemical staining of intact living rat pheochromocytoma PC12 cells. A. Extracellular staining of cells using Anti-P2Y1 Receptor (extracellular) antibody, (1:50) followed by goat anti-rabbit-AlexaFluor-594 secondary antibody (red). B. Merge of extracellular staining with live view of the cells.

GTX16924_FACS_18121410_199.jpg

GTX16924 FACS Image

Anti-P2Y1_Receptor_(extracellular) - Indirect flow cytometry analysis of Jurkat (human acute T cell leukemia) living cells: ___ Unstained cells.___ Cells stained + Anti-P2Y1 Receptor (extracellular) antibody, (5 μg/5x105 cells).

GTX16924_WB_18121410_679.jpg

GTX16924 WB Image

Anti-P2Y1_Receptor_(extracellular) - Western blot analysis of rat brain (lanes 1 and 4), Jurkat (lanes 2 and 5) and K-562 (lanes 3 and 6) lysates: 1-3. Anti-P2Y1 Receptor (extracellular) antibody, (1:200). 4-6. Anti-P2Y1 Receptor (extracellular) antibody, preincubated with the control peptide antigen.

GTX16924_IHC_18121410_166.jpg

GTX16924 IHC Image

Anti-P2Y1_Receptor_(extracellular) - Expression of P2Y1 in mouse hippocampus Immunohistochemical staining of mouse hippocampal CA3 region using Anti-P2Y1 (extracellular) antibody. A. P2Y1 staining (red) appears in the pyramidal layer (arrows). B. Nuclei staining using DAPI as the counterstain (blue). C. Merged images of panels A and B.

Package List Price ($)
$ 329