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P2Y1 antibody

Anti-P2Y1 antibody used in Western Blot (WB). GTX54795
Anti-P2Y1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54795

Cat. No. GTX54795

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS, IP

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all P2Y1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

42 kDa. ( Note )

Predict Reactivity

Bovine, Chicken, Turkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide (C)RALI YKDLD NSPLR RKS, corresponding to residues 242-258 (3rd  intracellular loop (i3) between TM5 and TM6 domains) of rat or human P2RY1. (Accession  : P49651, P47900).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

purinergic receptor P2Y1 , P2Y1 , SARCC

Cellular Localization

Cell membrane

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-P2Y1 antibody used in Western Blot (WB). GTX54795

GTX54795 WB Image

WB analysis of rat brain membrane (lanes 1, 3)  and human platelets (lanes 2, 4) lysates using GTX54795 P2Y1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-P2Y1 antibody used in IHC (Paraffin sections) (IHC-P). GTX54795

GTX54795 IHC-P Image

IHC-P analysis of rat thalamus tissue using GTX54795 P2Y1 antibody. Specific staining is black. Cresyl violet is used as the counterstain.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639