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P2Y11 antibody [C2C3], C-term

Orthogonal
Anti-P2Y11 antibody [C2C3], C-term used in Western Blot (WB). GTX108241
Anti-P2Y11 antibody [C2C3], C-term used in Western Blot (WB). GTX108241
Anti-P2Y11 antibody [C2C3], C-term used in IHC (Frozen sections) (IHC-Fr). GTX108241
Anti-P2Y11 antibody [C2C3], C-term used in IHC (Frozen sections) (IHC-Fr). GTX108241

Cat. No. GTX108241

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Human, Mouse
Package
100 μl ($399),
25 μl ($169)
See all P2Y11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Positive Control

Raji

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide encompassing a sequence within the Intracellular domain of human P2Y11. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1951088

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

purinergic receptor P2Y11 , P2Y11

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-P2Y11 antibody [C2C3], C-term used in Western Blot (WB). GTX108241

GTX108241 WB Image

Orthogonal

Boiled and unboiled Raji whole cell and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with P2Y11 antibody [C2C3], C-term (GTX108241) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. (WCE: whole cell extract; ME: membrane extract)
The observed M.W. is based on the publication: PMID: 31406184

Anti-P2Y11 antibody [C2C3], C-term used in Western Blot (WB). GTX108241

GTX108241 WB Image

Orthogonal

Non-transfected (–) and transfected (+) boiled and unboiled 293T whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with P2Y11 antibody [C2C3], C-term (GTX108241) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.

Anti-P2Y11 antibody [C2C3], C-term used in IHC (Frozen sections) (IHC-Fr). GTX108241

GTX108241 IHC-Fr Image

The data was published in the journal Cell Tissue Res in 2017.PMID: 28547658

Anti-P2Y11 antibody [C2C3], C-term used in IHC (Frozen sections) (IHC-Fr). GTX108241

GTX108241 IHC-Fr Image

The data was published in the journal Cell Tissue Res in 2017.PMID: 28547658

REFERENCE

Application Reference

Lommen J et al. Cell Tissue Res 2017; (Epub) Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus.
Application : IHC-Fr
Reactivity : Mouse
Helenius MH et al. Am J Physiol Lung Cell Mol Physiol 2015; 308 (10) : L1046-57 Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension.
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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169