GeneTex
United States (US)

P2Y11 antibody

GTX16872_ICCIF_18121410_185.jpg
GTX16872_WB_18121410_125.jpg

Cat No. GTX16872

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, FACS
Reactivity Human
APPLICATION

Calculated MW

40 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide (C)NATAAPKPSEPQSRELS, corresponding to amino acid residues 357-373 of human P2Y11 (Accession Q96G91). Intracellular, C-terminus.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Purinergic Receptor P2Y11,P2Y11,P2Ry11

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX16872_ICCIF_18121410_185.jpg

GTX16872 ICC/IF Image

Anti-P2Y11_Receptor - Expression of P2Y11 receptor in human P2Y11-MDCK transfected cells Immunocytochemical staining of paraformaldehyde-fixed and permeabilized human P2Y11-MDCK transfected cells. A. Staining using Anti-P2Y11 Receptor antibody, (1:200), followed by Alexa-488-conjugated goat-anti-rabbit secondary antibody. B. Nuclear fluorescence staining of cells using the membrane-permeable DNA dye Hoechst 33342. C. Merged images of panels A and B.

GTX16872_WB_18121410_125.jpg

GTX16872 WB Image

Anti-P2Y11_Receptor - Western blot analysis human platelet lysates: 1. Anti-P2Y11 Receptor antibody, (1:200). 2. Anti-P2Y11 Receptor antibody, preincubated with the control peptide antigen.

REFERENCE
Package List Price ($)
$ 329