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P2Y11 antibody

Anti-P2Y11 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16872
Anti-P2Y11 antibody used in Western Blot (WB). GTX16872

Cat. No. GTX16872

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, FACS, IP

Reactivity

 Human
Package
50 μl ($639)
See all P2Y11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
FACS Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Product Note

We do not recommend use of this product for Mouse,Rat samples.

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.9 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide (C)NATAAPKPSEPQSRELS, corresponding to amino acid residues 357-373 (Intracellular, C-terminus) of human P2RY11 (Accession  : Q96G91).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887548

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

purinergic receptor P2Y11 , P2Y11

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-P2Y11 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX16872

GTX16872 ICC/IF Image

ICC/IF analysis of PFA-fixed human P2Y11-MDCK transfected cells using GTX16872 P2Y11 antibody.
Panel A : Primary antibody
Panel B : DNA dye Hoechst 33342
Panel C : Merged images of panels A and B
Dilution : 1:200

Anti-P2Y11 antibody used in Western Blot (WB). GTX16872

GTX16872 WB Image

WB analysis of human platelet lysates using GTX16872 P2Y11 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

Application Reference

Avanzato D et al. Sci Rep 2016; 6 : 32602 Activation of P2X7 and P2Y11 purinergic receptors inhibits migration and normalizes tumor-derived endothelial cells via cAMP signaling.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639