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P2Y12 antibody

Overexpression
Anti-P2Y12 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13373
Anti-P2Y12 antibody used in IHC (Paraffin sections) (IHC-P). GTX13373
Anti-P2Y12 antibody used in IHC (Paraffin sections) (IHC-P). GTX13373

Cat. No. GTX13373

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P

Reactivity

 Human
Package
25 μg ($399)
See all P2Y12 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 32 μg/ml
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Predict Reactivity

Pig, Monkey, Gibbon, Gorilla, Marmoset(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human P2RY12 / P2Y12.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

purinergic receptor P2Y12 , ADPGR , BDPLT8 , HORK3 , P2RY12 , P2T(AC) , P2Y(12)R , P2Y(AC) , P2Y(ADP) , P2Y(cyc) , P2Y12 , SP1999

Cellular Localization

Cell membrane

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

Database

Research Area

DATA IMAGES

Anti-P2Y12 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX13373

GTX13373 ICC/IF Image

Overexpression

ICC/IF analysis of HEK293 transfected with P2Y12 using GTX13373 P2Y12 antibody.

Anti-P2Y12 antibody used in IHC (Paraffin sections) (IHC-P). GTX13373

GTX13373 IHC-P Image

IHC-P analysis of human brain, glioblastoma tissue using GTX13373 P2Y12 antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-P2Y12 antibody used in IHC (Paraffin sections) (IHC-P). GTX13373

GTX13373 IHC-P Image

IHC-P analysis of human blood, platelets tissue using GTX13373 P2Y12 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399