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PACAP antibody

Anti-PACAP antibody used in IHC (Frozen sections) (IHC-Fr). GTX37576
Anti-PACAP antibody used in IHC (Paraffin sections) (IHC-P). GTX37576
Anti-PACAP antibody used in Western Blot (WB). GTX37576
Anti-PACAP antibody used in IHC (Paraffin sections) (IHC-P). GTX37576

Cat. No. GTX37576

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr, IHC

Reactivity

 Rat
Package
100 μg ($399)
See all PACAP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P 1:400-800
IHC-Fr Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 41-28 amino acids of human PACAP 38

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11178319

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adenylate cyclase activating polypeptide 1 , PACAP

Cellular Localization

Secreted

Background

This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]

Database

  • Gene ID: 116 ADCYAP1
  • UniProt: P18509 ADCYAP1

Research Area

DATA IMAGES

Anti-PACAP antibody used in IHC (Frozen sections) (IHC-Fr). GTX37576

GTX37576 IHC-Fr Image

IHC-Fr analysis of rat brain tissue using GTX37576 PACAP antibody.

Anti-PACAP antibody used in IHC (Paraffin sections) (IHC-P). GTX37576

GTX37576 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37576 PACAP antibody.

Anti-PACAP antibody used in Western Blot (WB). GTX37576

GTX37576 WB Image

WB analysis of rat brain (Lane 1) and rat heart (Lane 2) tissue lysates using GTX37576 PACAP antibody.

Anti-PACAP antibody used in IHC (Paraffin sections) (IHC-P). GTX37576

GTX37576 IHC-P Image

The data was published in the journal Int J Mol Sci in 2015. PMID: 25782157

REFERENCE

Application Reference

Broome ST et al. J Mol Neurosci 2023; 73 (9月10日) : 724-737 Early Alterations of PACAP and VIP Expression in the Female Rat Brain Following Spinal Cord Injury.
Broome ST et al. J Mol Neurosci 2022; 72 (11) : 2163-2175 PACAP and VIP Mitigate Rotenone-Induced Inflammation in BV-2 Microglial Cells.
Giunta S et al. Int J Mol Sci 2015; 16 (3) : 5922-44 Ameliorative effects of PACAP against cartilage degeneration. Morphological, immunohistochemical and biochemical evidence from in vivo and in vitro models of rat osteoarthritis.
Application : IHC
Reactivity : Rat
Submit a Reference

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399