GeneTex
United States (US)

PACS1 antibody

Anti-PACS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32158
Anti-PACS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32158
Anti-PACS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32158
Anti-PACS1 antibody used in Western Blot (WB). GTX32158

Cat No. GTX32158

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

105 kDa. ( Note )

Positive Control

Rat Bladder Tissue Lysate(GTX24031)

Specificity/Sensitivity

PACS1 antibody is human, mouse and rat reactive. Multiple isoforms of PACS1 are known to exist. PACS1 antibody is predicted to not cross-react with PACS2.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PACS1 antibody was raised against a 17 amino acid peptide near the center of human PACS1.The immunogen is located within amino acids 430 - 480 of PACS1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Phosphofurin Acidic Cluster Sorting Protein 1,Mrd17,Shms,Pacs1

Background

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
Anti-PACS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32158

GTX32158 IHC-P Image

IHC-P analysis of human bladder tissue using GTX32158 PACS1 antibody.
Working concentration : 20 μg/ml

Anti-PACS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32158

GTX32158 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32158 PACS1 antibody.
Working concentration : 2 μg/ml

Anti-PACS1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32158

GTX32158 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32158 PACS1 antibody.
Working concentration : 20 μg/ml

Anti-PACS1 antibody used in Western Blot (WB). GTX32158

GTX32158 WB Image

WB analysis of rat bladder tissue lysate using GTX32158 PACS1 antibody.
Working concentration : 1 μg/ml

Package List Price ($)
$ 329