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United States (US)

PAI-1 antibody [3E529]

Cat No. GTX40286

Host Mouse
Clonality Monoclonal
Clone Name 3E529
Isotype IgG
Application ELISA
Reactivity Human
Package
100 μg ($329)
See all PAI-1 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ELISA Assay dependent
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

Specificity/Sensitivity

Recognizes both free and complexed forms of Human PAI-1.
PROPERTIES

Form

Liquid

Buffer

0.05M Sodium Phosphate 0.1M sodium chloride, 1mM EDTA, pH 6.6

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.10 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human PAI

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Serpin Family E Member 1,Pai,Pai-1,Pai1,Planh1,Serpine1

Cellular Localization

Secreted

Background

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Database

Research Area

REFERENCE
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REVIEW
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Package List Price ($)
$ 329