GeneTex
United States (US)

PAK3 (phospho Ser154) antibody

GTX32232_20190131_WB_19013101_972.jpg

Cat No. GTX32232

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

62 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of PAK3. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

P21 (Rac1) Activated Kinase 3,Ara,Mrx30,Mrx47,Ophn3,Pak-3,Pak3Beta,Bpak,Beta-Pak,Pak3

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2017]

Database

Research Area

DATA IMAGES
GTX32232_20190131_WB_19013101_972.jpg

GTX32232 WB Image

WB analysis of EGF-treated HEK293T (A), NIH3T3 (B), mouse brain (C), EGF-treated SP2/0 (D), EGF-treated H9C2 (E) whole cell lysates using GTX32232 PAK3 (phospho Ser154) antibody.

Package List Price ($)
$ 319