APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 5 μg/ml |
Not tested in other applications.
Predict Reactivity
Monkey, Gibbon, Gorilla, Marmoset, Orangutan(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 20 amino acid peptide from internal region of human PAK7.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375986
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
p21 (RAC1) activated kinase 5 , PAK5 , PAK7
Cellular Localization
Mitochondrion,Cytoplasm,Nucleus
Background
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
|
GTX71887 IHC-P Image
IHC-P analysis of human pancreas tissue using GTX71887 PAK5 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX71887 IHC-P Image
IHC-P analysis of human brain, substantia nigra neurons tissue using GTX71887 PAK5 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
|
|
GTX71887 IHC-P Image
IHC-P analysis of human brain, thalamus neurons tissue using GTX71887 PAK5 antibody.
Antigen retrieval : Heat-induced antigen retrieval
|
REFERENCE
There are currently no references for PAK5 antibody (GTX71887). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PAK5 antibody (GTX71887). Be the first to share your experience with this product.
