GeneTex
United States (US)

PAK6 antibody

GTX31672_267_ICC-IF_20180221_18121410_769.jpg
GTX31672_266_ICC-IF_20180221_18121410_227.jpg
GTX31672_2846_WB_20180221_18121410_286.jpg

Cat No. GTX31672

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 4 μg/mL
ICC/IF 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

75 kDa. ( Note )

Positive Control

Raji Cell Slide(GTX25538) , Raji Cell Lysate(GTX27908)

Specificity/Sensitivity

PAK6 antibody is predicted to not cross-react with other PAK family proteins.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

PAK6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human PAK6.The immunogen is located within amino acids 260 - 310 of PAK6.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

P21 (Rac1) Activated Kinase 6,Pak5,Pak6

Background

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Database

Research Area

DATA IMAGES
GTX31672_267_ICC-IF_20180221_18121410_769.jpg

GTX31672 ICC/IF Image

ICC/IF analysis of Raji cells using GTX31672 PAK6 antibody.
Working concentration : 10 μg/ml

GTX31672_266_ICC-IF_20180221_18121410_227.jpg

GTX31672 ICC/IF Image

ICC/IF analysis of Raji cells using GTX31672 PAK6 antibody.
Working concentration : 10 μg/ml

GTX31672_2846_WB_20180221_18121410_286.jpg

GTX31672 WB Image

WB analysis of Raji cell lysate using GTX31672 PAK6 antibody.
Working concentration : (A) 1, (B) 2, and (C) 4 μg/ml

Package List Price ($)
$ 329