GeneTex
United States (US)

PAK6 antibody

GTX33383_20180530_WB_18121410_450.jpg
GTX33383_20180530_IHC-P_18121410_323.jpg

Cat No. GTX33383

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

75 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PAK6 (NP_064553.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

P21 (Rac1) Activated Kinase 6,Pak5,Pak6

Background

This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Database

Research Area

DATA IMAGES
GTX33383_20180530_WB_18121410_450.jpg

GTX33383 WB Image

WB analysis of various samples using GTX33383 PAK6 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX33383_20180530_IHC-P_18121410_323.jpg

GTX33383 IHC-P Image

IHC-P analysis of human brain cancer tissue using GTX33383 PAK6 antibody.
Dilution : 1:100

Package List Price ($)
$ 329