Application Note
Western blot - Use at 1:250-1:500 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Product Note
Reacts with residues 399-418 (SPWSELEFQFPDDKDPVWEF) of the mouse PAPK protein.
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Purification
Affinity purified IgG
Conjugation
Unconjugated
RRID
AB_383260
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Background
A novel protein kinase, polyploidy-associated protein kinase (PAPK) is a new member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival. Activation of a death signal transduction pathway may result in the stimulation of the PAPK promoter, which leads to increased PAPK expression and provides a negative feedback signal that prevents cell death.
Research Area