GeneTex

  • Country / Location Selection

United States (US)

PAPP A antibody [10E2]

Cat. No. GTX28347

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10E2

Isotype

 IgG2b

Application

 WB, ELISA, Immunoassay

Reactivity

 Human
Package
100 μg ($399)
See all PAPP A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ELISA Assay dependent
Immunoassay Assay dependent
Not tested in other applications.

Calculated MW

181 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human PAPP-A antigen

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

pappalysin 1 , ASBABP2 , DIPLA1 , IGFBP-4ase , PAPA , PAPP-A , PAPPA1

Cellular Localization

Secreted

Background

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. [provided by RefSeq, Aug 2017]

Database

Research Area

REFERENCE

There are currently no references for PAPP A antibody [10E2] (GTX28347). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for PAPP A antibody [10E2] (GTX28347). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399