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PAPP A antibody [18A10]

Anti-PAPP A antibody [18A10] used in Western Blot (WB). GTX10196

Cat No. GTX10196

Host Mouse
Clonality Monoclonal
Clone Name 18A10
Isotype IgG2a
Application WB, ELISA
Reactivity Human
Package
100 μg ($219)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

73.52 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 0.09 % sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.

Concentration

Batch dependent

Antigen Species

Human

Immunogen

Purified human PAPPA antigen

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Pappalysin 1 , Asbabp2 , Dipla1 , Igfbp-4Ase , Papa , Papp-A , Pappa1 , Pappa

Background

This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-PAPP A antibody [18A10] used in Western Blot (WB). GTX10196

GTX10196 WB Image

Detection of human PAPP-A and proMBP subunits of htPAPP-A by monoclonal antibodies in Western blot. Lane 1: PAPP A antibody [18A10] (GTX10196); Lane 2: PAPP A antibody [3C8] (GTX10194); Lane 3: PAPP A antibody [5H9] (GTX10191); Lane 4: PAPP A antibody [11E4] (GTX14597); Lane 5: PAPP A antibody [10A5] (GTX10193); Lane 6: PAPP A antibody [3C8] (GTX10194); Lanes 1-4: reducing conditions; Lanes 5-6: non-reducing conditions, heterotetrameric complex was detected by PAPP A antibody [10A5] (GTX10193) and PAPP A antibody [3C8] (GTX10194)

REFERENCE
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REVIEW
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Package List Price ($)
$ 219