GeneTex
United States (US)

PAPP A antibody [18A10]

PAPP-A-antibody-18A10_Western blot_GTX10196-1_19011720_454.jpg

Cat No. GTX10196

Host Mouse
Clonality Monoclonal
Clone Name 18A10
Isotype IgG2a
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 200 kDa under reducing conditions. (predicted molecular weight: 195 kDa). Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

181 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Purified human PAPPA antigen

Purification

Protein A purified
Purified by chromatography on protein A. Purity tested by electrophoresis

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1, PAPP A, IGFBP 4ase, PAPPA, IGFBP4ase

Background

Pregnancy-associated plasma protein A (PAPPA) is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.

Database

DATA IMAGES
PAPP-A-antibody-18A10_Western blot_GTX10196-1_19011720_454.jpg

GTX10196 WB Image

Detection of human PAPP-A and proMBP subunits of htPAPP-A by monoclonal antibodies in Western blot. Lane 1: PAPP A antibody [18A10] (GTX10196); Lane 2: PAPP A antibody [3C8] (GTX10194); Lane 3: PAPP A antibody [5H9] (GTX10191); Lane 4: PAPP A antibody [11E4] (GTX14597); Lane 5: PAPP A antibody [10A5] (GTX10193); Lane 6: PAPP A antibody [3C8] (GTX10194); Lanes 1-4: reducing conditions; Lanes 5-6: non-reducing conditions, heterotetrameric complex was detected by PAPP A antibody [10A5] (GTX10193) and PAPP A antibody [3C8] (GTX10194)

Package List Price ($)
$ 219